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Product Name
Human P4HB/ERBA2L/PDI/PDIA1/PO4DB (His tag) recombinant protein
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Description
Protein Disulfide-Isomerase (P4HB) is an endoplasmic reticulum lumen protein that belongs to the protein disulfide isomerase family. P4HB contains two thioredoxin domains and catalyzes the formation, breakage, and rearrangement of -S-S- bonds in proteins. P4HB is involved in hydroxylation of prolyl residues in preprocollagen. P4HB has the ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner. P4HB plays a role in both the influx and efflux of S-nitrosothiol-bound nitric oxide.
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Protein name
prolyl 4-hydroxylase subunit beta(P4HB)
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Protein short names
ERBA2L; PDI; PDIA1; PO4DB
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Uniprot ID
P07237
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human P4HB/ERBA2L/PDI/PDIA1/PO4DB Asp18-Lys505 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human P4HB/ERBA2L/PDI/PDIA1/PO4DB (His tag) recombinant protein
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