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Product Name
Human MPZL1/PZR/UNQ849/PRO1787 (His tag) recombinant protein
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Description
Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.
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Protein name
myelin protein zero like 1(MPZL1)
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Protein short names
PZR; UNQ849; PRO1787
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Uniprot ID
O95297
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human MPZL1/PZR/UNQ849/PRO1787 Ser36-Val162 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human MPZL1/PZR/UNQ849/PRO1787 (His tag) recombinant protein
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