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Product Name
Human MOG recombinant protein
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Description
Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
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Protein name
myelin oligodendrocyte glycoprotein(MOG)
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Uniprot ID
Q16653
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human MOG Gly30-Gly154 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human MOG recombinant protein
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