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Human MGEA5 Recombinant protein (His tag)

Cat.#: 509916

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human MGEA5 Recombinant protein (His tag)
  • Documents
  • Description
    Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714). {PubMed:11148210, PubMed:11788610, PubMed:20673219, PubMed:22365600, PubMed:24088714}.; Isoform 3: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1. {PubMed:20673219}.
  • Protein name
    Protein O-GlcNAcase
  • Protein short names
    HEXC; KIAA0679; MEA5
  • Uniprot ID
    O60502
  • Gene Name
    MGEA5; HEXC; KIAA0679; MEA5
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human MGEA5 (NP_001135906.1) 1-350 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human MGEA5 SDS-PAGE

    Recombinant human MGEA5 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"