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Product Name
Human MECR/NBRF1/CGI-63 (His tag) recombinant protein
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Description
Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lower levels in the placenta, liver, kidney and pancreas, with weakly or no expression in the lung. MECR exists as a homodimer, which catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. MECR may take part in the mitochondrial synthesis of fatty acids.
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Protein name
mitochondrial trans-2-enoyl-CoA reductase(MECR)
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Protein short names
NBRF1; CGI-63
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Uniprot ID
Q9BV79
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human MECR/NBRF1/CGI-63 Pro54-Met373 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human MECR/NBRF1/CGI-63 (His tag) recombinant protein
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