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Product Name
Human LYVE1/CRSBP1/HAR/XLKD1 (His tag) recombinant protein
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Description
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
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Protein name
lymphatic vessel endothelial hyaluronan receptor 1(LYVE1)
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Protein short names
CRSBP1; HAR; XLKD1; UNQ230; PRO263
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Uniprot ID
Q9Y5Y7
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human LYVE1/CRSBP1/HAR/XLKD1 Leu20-Thr238 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human LYVE1/CRSBP1/HAR/XLKD1 (His tag) recombinant protein
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