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Product Name
Human LTA/TNFB/TNFSF1 recombinant protein
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Description
Tumor Necrosis Factor β (TNF-β) is a secreted protein belonging to the tumor necrosis factor family. TNF-β binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF-β forms heterotrimers with lymphotoxin-beta, which anchors TNF-β to the cell surface. TNF-β mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.
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Protein name
lymphotoxin alpha(LTA)
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Protein short names
TNFB; TNFSF1
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Uniprot ID
P01374
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human LTA/TNFB/TNFSF1 Leu35-Leu205 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human LTA/TNFB/TNFSF1 recombinant protein
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