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Product Name
Human LEFTY1/LEFTB/LEFTYB/UNQ278/PRO317 recombinant protein
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Description
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functions both in vivo and in vitro, including mitogenesis, cellular migration, differentiation, angiogenesis, and wound healing. Human embryonic stem cell (hESC) cultures require FGF basic (also known as FGF-2 or bFGF) in cell culture media to remain in an undifferentiated and pluripotent state. Thermostable FGF basic was engineered for enhanced stability in culture media, without modification of its biological function. FGF basic is a required component of stem cell culture media for maintaining cells in an undifferentiated state. Because FGF basic is unstable, daily media changes are needed. The thermostable FGF basic that supports a 2-day media change schedule, so no media changes are required over a weekend. This thermostable FGF basic was more stable than FGF basic in biochemical studies, and maintained cell growth, pluripotency and differentiation potential with a 2-day feeding schedule.
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Protein name
left-right determination factor 1(LEFTY1)
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Protein short names
LEFTB; LEFTYB; UNQ278; PRO317
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Uniprot ID
O75610
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human LEFTY1/LEFTB/LEFTYB/UNQ278/PRO317 Met1-Ser155 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human LEFTY1/LEFTB/LEFTYB/UNQ278/PRO317 recombinant protein
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"