Human KIR2DL4/CD158D/KIR103AS (His tag) recombinant protein

Human KIR2DL4/CD158D/KIR103AS (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.

killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4(KIR2DL4)

CD158D; KIR103AS

Q99706

Human Cells

A DNA sequence encoding the Human KIR2DL4/CD158D/KIR103AS Trp22-His242 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.