Human KIAA0776 Recombinant protein (His tag)

Cat.#: 509279

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Product Information

  • Product Name
    Human KIAA0776 Recombinant protein (His tag)
  • Documents
  • Description
    E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling (PubMed:20018847, PubMed:20164180, PubMed:20228063, PubMed:25219498). May also through TRIP4 ufmylation play a role in nuclear receptors-mediated transcription (PubMed:25219498). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress (PubMed:23152784). {PubMed:20018847, PubMed:20164180, PubMed:20228063, PubMed:23152784, PubMed:25219498}.
  • Protein name
    E3 UFM1-protein ligase 1
  • Protein short names
    KIAA0776; NLBP; RCAD
  • Uniprot ID
    O94874
  • Gene Name
    UFL1; KIAA0776; NLBP; RCAD
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human UFL1 (NP_056138.1) 1-350 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human KIAA0776 SDS-PAGE

    Recombinant human KIAA0776 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"