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Product Name
Human ITLN1/INTL/ITLN/LFR/UNQ640/PRO1270 (His tag) recombinant protein
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Description
Intelectin-1(ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.
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Protein name
intelectin 1(ITLN1)
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Protein short names
INTL; ITLN; LFR; UNQ640; PRO1270
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Uniprot ID
Q8WWA0
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ITLN1/INTL/ITLN/LFR/UNQ640/PRO1270 Thr19-Ser298 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ITLN1/INTL/ITLN/LFR/UNQ640/PRO1270 (His tag) recombinant protein
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