Human Interferon alpha-B / IFNA8 (His Tag) recombinant protein

Human Interferon alpha-B / IFNA8 (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumorcells. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They also allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. Interferons also activate immune cells, such as natural killer cells and macrophages. They increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes. They also increase the ability of uninfected host cells to resist new infection by virus. Certain symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Produced by macrophages, IFN-alpha have antiviral activities.

Interferon alpha-8

LEIF B; INTERFERON ALPHA FAMILY; INTERFERON ALPHA-B; GENE 8; INTERFERON ALPHA TYPE 201; INTERFERON ALPHA-B2; IFA6; RP11-354P17.14-001; INTERFERON; INTERFERON ALPHA-B'; IFNA8/6; IFN-ALPHA-8; IFN-ALPHAB; INTERFERON ALPHA-8; IFNA8; IFA8; ALPHA 8

P32881

IFNA8

Human Cells

A DNA sequence encoding the human IFNA8 (NP_002161.2) (Met1-Glu189) was expressed with a C-terminal polyhistidine tag.

Human

The recombinant human IFNA8 comprises 177 amino acids and has a predicted molecular mass of 20.9 kDa. The apparent molecular mass of the protein is approximately 28 kDa in SDS-PAGE under reducing conditions.

> 90 % as determined by SDS-PAGE