Human Interferon alpha-B / IFNA8 (His Tag) recombinant protein

Cat.#: 503376

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Product Information

  • Product Name
    Human Interferon alpha-B / IFNA8 (His Tag) recombinant protein
  • Documents
  • Description
    Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumorcells. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They also allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. Interferons also activate immune cells, such as natural killer cells and macrophages. They increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes. They also increase the ability of uninfected host cells to resist new infection by virus. Certain symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Produced by macrophages, IFN-alpha have antiviral activities.
  • Protein name
    Interferon alpha-8
  • Protein short names
    LEIF B; INTERFERON ALPHA FAMILY; INTERFERON ALPHA-B; GENE 8; INTERFERON ALPHA TYPE 201; INTERFERON ALPHA-B2; IFA6; RP11-354P17.14-001; INTERFERON; INTERFERON ALPHA-B'; IFNA8/6; IFN-ALPHA-8; IFN-ALPHAB; INTERFERON ALPHA-8; IFNA8; IFA8; ALPHA 8
  • Uniprot ID
    P32881
  • Gene Name
    IFNA8
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human IFNA8 (NP_002161.2) (Met1-Glu189) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IFNA8 comprises 177 amino acids and has a predicted molecular mass of 20.9 kDa. The apparent molecular mass of the protein is approximately 28 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Human Interferon alpha-B / IFNA8 Protein (His Tag) SDS-PAGE

    Human Interferon alpha-B / IFNA8 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"