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Product Name
Human IMPA2/IMP.18P (His tag) recombinant protein
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Description
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.
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Protein name
inositol monophosphatase 2(IMPA2)
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Protein short names
IMP.18P
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Uniprot ID
O14732
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IMPA2/IMP.18P Met1-Lys288 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human IMPA2/IMP.18P (His tag) recombinant protein
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