Human GSS (His tag) recombinant protein

Human GSS (His tag) recombinant protein

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• Material Safety Data Sheets (MSDS)

Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

glutathione synthetase(GSS)

P48637

E. coli

A DNA sequence encoding the Human GSS Ala2-Val474 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.