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Product Name
Human GMPR / GMPR1 (His Tag) recombinant protein
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Description
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family. This family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved in purine metabolism and adopt a TIM barrel structure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
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Protein short names
GUANINE MONOPHOSPHATE REDUCTASE; AV028449; GMPR1; GMPR; GUANOSINE 5'-MONOPHOSPHATE OXIDOREDUCTASE 1; GUANOSINE MONOPHOSPHATE REDUCTASE; GUANOSINE MONOPHOSPHATE REDUCTASE 1; 2310004P21RIK; RP3-467D16.2; GMP REDUCTASE 1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human GMPR (Met1-Ser345) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human GMPR consists of 360 amino acids and predicts a molecular mass of 39.2 KDa. It migrates as an approximately 37 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human GMPR / GMPR1 Protein (His Tag) SDS-PAGE
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