-
Product Name
Human GMFB recombinant protein
- Documents
-
Description
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
-
Protein short names
3110001O16RIK; AI851627; GMF-BETA; GLIA MATURATION FACTOR BETA; D14ERTD630E; 3110001H22RIK; C79176; GMF
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human GMFB (Met1-His142) was expressed.
-
Protein Species
Human
-
Molecular weight
The recombinant human GMFB consists of 142 amino acids and predicts a molecular mass of 16.7 KDa. It migrates as an approximately 17 KDa band in SDS-PAGE under reducing conditions.
-
Purity
> 95 % as determined by SDS-PAGE
-
Validations
Human GMFB Protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"