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Product Name
Human GCDH (His tag) recombinant protein
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Description
Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.
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Protein name
glutaryl-CoA dehydrogenase(GCDH)
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Uniprot ID
Q92947
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human GCDH Arg45-Lys438 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human GCDH (His tag) recombinant protein
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