Human GATE-16 / GABARAPL2 (His Tag) recombinant protein

Human GATE-16 / GABARAPL2 (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.

2900019O08RIK; UBIQUITIN ASSOCIATED AND SH3 DOMAIN CONTAINING; STS-1; GATE-16; UBIQUITIN ASSOCIATED AND SH3 DOMAIN CONTAINING B; TYROSINE-PROTEIN PHOSPHATASE STS1/TULA2; CBL-INTERACTING PROTEIN STS-1; ATG8C; P70; AI173605; ATG8; B; GEF2; UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN B; GATE16; NM23-PHOSPHORYLATED UNKNOWN SUBSTRATE; 2810457I06RIK; 0610012F20RIK; T-CELL UBIQUITIN LIGAND 2; UBASH3B; STS1; TULA-2; BB125008; SUPPRESSOR OF T-CELL RECEPTOR SIGNALING 1; SH3 DOMAIN-CONTAINING 70 KDA PROTEIN; GEF-2; CBL-INTERACTING PROTEIN P70

E. coli

A DNA sequence encoding the mature form of human GABARAPL2\(P60520) (Met1-Phe117) was expressed with a polyhistide tag at the N-terminus.

Human

The recombinant human GABARAPL2 consists of 132 amino acids and predicts a molecular mass of 15.5 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions.

> 95 % as determined by SDS-PAGE