Human FLRT2/KIAA0405/UNQ232/PRO265 (His tag) recombinant protein

Human FLRT2/KIAA0405/UNQ232/PRO265 (His tag) recombinant protein

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Fibronectin Leucine Rich Transmembrane protein 2 (FLRT2) is a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1, FLRT2 and FLRT3, all contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell cell association. FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome, suggesting its involvement in the FGF signalling pathway.

fibronectin leucine rich transmembrane protein 2(FLRT2)

KIAA0405; UNQ232; PRO265

O43155

Human Cells

A DNA sequence encoding the Human FLRT2/KIAA0405/UNQ232/PRO265 Cys36-Ser539 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.