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Product Name
Human EGR1/KROX24/ZNF225 (His tag) recombinant protein
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Description
EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of synaptobrevin II (a protein important for synaptic exocytosis).
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Protein name
early growth response 1(EGR1)
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Protein short names
KROX24; ZNF225
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Uniprot ID
P18146
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human EGR1/KROX24/ZNF225 Gln282-Ser433 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human EGR1/KROX24/ZNF225 (His tag) recombinant protein
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