Human EGFL6 / EGF-L6 (Flag & His Tag) recombinant protein

Human EGFL6 / EGF-L6 (Flag & His Tag) recombinant protein

Cat.#: 503855

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Product Information

  • Product Name
    Human EGFL6 / EGF-L6 (Flag & His Tag) recombinant protein
  • Documents
  • Description
    EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. EGFL6 gene is expressed early during development, and its expression has been detected in lung and meningioma tumors.
  • Protein name
    Epidermal growth factor-like protein 6
  • Protein short names
    EGFL6; EGF-LIKE PROTEIN 6; MULTIPLE 6; EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6; MAEG; EGF REPEAT-CONTAINING PROTEIN 6; PP648; MAM AND EGF DOMAINS-CONTAINING GENE PROTEIN; MULTIPLE 6; MAM AND EGF DOMAIN CONTAINING; W80; EGF-LIKE-DOMAIN; RP23-408K4.7
  • Uniprot ID
    Q8IUX8
  • Gene Name
    EGFL6; MAEG; PP648; UNQ281/PRO320
  • Source/Expression Host
    Baculovirus-insect cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human EGFL6 (NP_056322.2) (Asn22-Asp553) was expressed with the flag tag at the N-terminus and the histidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human EGFL6 consists of 551 amino acids and has a calculated molecular mass of 61.5 kDa.
  • Purity
    > 65 % as determined by SDS-PAGE
  • Activity
    Measured by the ability of the immobilized protein to support the adhesion of NIH-3T3 mouse embryonic fibroblast cells.When 5 × 10E4 cells/well areadded to CD4 coated plates (1.25μg/mL and 100μL/well),approximately 40%-60% will adhere specifically after 30 minutes at 37℃.
  • Validations

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"