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Product Name
Human CXCL1/GRO/GRO1/GROA/MGSA/SCYB1 (His tag) recombinant protein
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Description
Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.
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Protein name
C-X-C motif chemokine ligand 1(CXCL1)
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Protein short names
GRO; GRO1; GROA; MGSA; SCYB1
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Uniprot ID
P09341
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CXCL1/GRO/GRO1/GROA/MGSA/SCYB1 Ala35-Asn107 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CXCL1/GRO/GRO1/GROA/MGSA/SCYB1 (His tag) recombinant protein
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