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Product Name
Human CSF3/C17orf33/GCSF recombinant protein
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Description
Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.
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Protein name
colony stimulating factor 3(CSF3)
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Protein short names
C17orf33; GCSF
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Uniprot ID
P09919-2
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CSF3/C17orf33/GCSF Thr31-Pro204 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CSF3/C17orf33/GCSF recombinant protein
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