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Product Name
Human CLEC4E/CLECSF9/MINCLE/UNQ218 (His tag) recombinant protein
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Description
C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional control of CEBPB. Human CLEC4E shares 67% sequence identity with its mouse counterpart, suggesting a similar function between species. CLEC-4E exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to a natural killer gene complex region on human chromosome 12.
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Protein name
C-type lectin domain family 4 member E(CLEC4E)
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Protein short names
CLECSF9; MINCLE; UNQ218; PRO244
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Uniprot ID
Q9ULY5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CLEC4E/CLECSF9/MINCLE/UNQ218 Arg41-Leu219 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CLEC4E/CLECSF9/MINCLE/UNQ218 (His tag) recombinant protein
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