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Product Name
Human CDKN1B/KIP1 (His tag) recombinant protein
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Description
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skeletal muscle. CDKN1B is a potent inhibitor of Cyclin E- and Cyclin A-CDK2 complexes. CDKN1B forms a complex with Cyclin Type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. In addition, CDKN1B acts as an inhibitor or an activator of Cyclin Type D-CDK4 complexes depending on its phosphorylation state and stoichometry.
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Protein name
cyclin dependent kinase inhibitor 1B(CDKN1B)
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Protein short names
KIP1
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Uniprot ID
P46527
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CDKN1B/KIP1 Met1-Thr198 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CDKN1B/KIP1 (His tag) recombinant protein
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