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Product Name
Human CDK2AP1/CDKAP1/DOC1 (His tag) recombinant protein
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Description
Cyclin-Dependent Kinase 2-Associated Protein 1 (CDK2AP1) is a member of the CDK2AP family. The homodimeric structure of CDK2AP1 includes an intrinsically disordered 60-residue N-terminal region and a four-helix bundle dimeric structure with reduced Cys-105 in the C-terminal region. The widely expressed CDK2AP1 protein is the only known specific inhibitor of CDK2, making it an important component of cell cycle regulation during G(1)-to-S phase transition. In addition, CDK2AP1 serves as a regulatory role in DNA replication during S phase of the cell cycle.
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Protein name
cyclin dependent kinase 2 associated protein 1(CDK2AP1)
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Protein short names
CDKAP1; DOC1
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Uniprot ID
O14519
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CDK2AP1/CDKAP1/DOC1 Met1-Ser115 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CDK2AP1/CDKAP1/DOC1 (His tag) recombinant protein
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