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Product Name
Human CD320/8D6A/UNQ198/PRO224 (Fc tag) recombinant protein
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Description
CD320 antigen is also known as 8D6 antigen，FDC-signaling molecule 8D6，Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
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Protein name
CD320 molecule(CD320)
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Protein short names
8D6A; UNQ198; PRO224
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Uniprot ID
Q9NPF0
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CD320/8D6A/UNQ198/PRO224 Ser36-Val231 is expressed with a Fc tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CD320/8D6A/UNQ198/PRO224 (Fc tag) recombinant protein
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