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Product Name
Human CD300C/CMRF35/CMRF35A (His tag) recombinant protein
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Description
CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
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Protein name
CD300c molecule(CD300C)
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Protein short names
CMRF35; CMRF35A; CMRF35A1; IGSF16
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Uniprot ID
Q08708
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CD300C/CMRF35/CMRF35A Gly21-Arg183 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CD300C/CMRF35/CMRF35A (His tag) recombinant protein
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