• Human CD177/NB1/PRV1/UNQ595/PRO1181 (His tag) recombinant protein

Human CD177/NB1/PRV1/UNQ595/PRO1181 (His tag) recombinant protein

Cat.#: 519828

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Product Information

  • Product Name
    Human CD177/NB1/PRV1/UNQ595/PRO1181 (His tag) recombinant protein
  • Documents
  • Description
    CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
  • Protein name
    CD177 molecule(CD177)
  • Protein short names
    NB1; PRV1; UNQ595; PRO1181
  • Uniprot ID
    Q8N6Q3
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CD177/NB1/PRV1/UNQ595/PRO1181 Leu22-Gly407 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CD177/NB1/PRV1/UNQ595/PRO1181 (His tag) recombinant protein

    Human CD177/NB1/PRV1/UNQ595/PRO1181 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"