Human CCL3L1/D17S1718/G0S19-2 (His tag) recombinant protein

Human CCL3L1/D17S1718/G0S19-2 (His tag) recombinant protein

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C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. The copy number of this gene varies among individuals: most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The human genome reference assembly contains two full copies of the gene (CCL3L3 and CCL3L1) and a partial pseudogene. This record represents the more centromeric full-length gene.

C-C motif chemokine ligand 3 like 3(CCL3L3)

D17S1718; G0S19-2; SCYA3L1; CCL3L3

P16619

Human Cells

A DNA sequence encoding the Human CCL3L1/D17S1718/G0S19-2 Ala24-Ala93 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.