• Human CCL26/SCYA26/UNQ216/PRO242 recombinant protein

Human CCL26/SCYA26/UNQ216/PRO242 recombinant protein

Cat.#: 518045

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Product Information

  • Product Name
    Human CCL26/SCYA26/UNQ216/PRO242 recombinant protein
  • Documents
  • Description
    Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
  • Protein name
    C-C motif chemokine ligand 26(CCL26)
  • Protein short names
    SCYA26; UNQ216; PRO242
  • Uniprot ID
    Q9Y258
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CCL26/SCYA26/UNQ216/PRO242 Thr24-Leu94 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CCL26/SCYA26/UNQ216/PRO242 recombinant protein

    Human CCL26/SCYA26/UNQ216/PRO242 recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"