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Product Name
Human CCL23 / MIP 3 (His Tag) recombinant protein
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Description
CCL23, also known as MIP 3, is a small cytokine which belongs to the CC chemokine family. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL23 is predominantly expressed in lung and liver tissue, but also can be detected in bone marrow and placenta. It displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. CCL23 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
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Protein name
C-C motif chemokine 23
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Protein short names
MEMBER 23; SCYA23; SMALL INDUCIBLE CYTOKINE SUBFAMILY A (CYS-CYS); SMALL-INDUCIBLE CYTOKINE A23; MYELOID PROGENITOR INHIBITORY FACTOR 1; C-C MOTIF CHEMOKINE 23; CKB8; MIP3; MIP-3; CCL23; CHEMOKINE (C-C MOTIF) LIGAND 23; HMRP-2A; MPIF-1; MACROPHAGE INFLAMMATORY PROTEIN 3; C6 BETA-CHEMOKINE; CKB-8-1; CK-BETA-8; CKB-8
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Uniprot ID
P55773
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Gene Name
CCL23; MIP3; MPIF1; SCYA23
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CCL23 (AAB51134.1) (Arg22-Asn120) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CCL23 consists of 115 amino acids and predicts a molecular mass of 13.5 KDa. It migrates as an approximately 16-20 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CCL23 / MIP 3 Protein (His Tag) SDS-PAGE
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