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Product Name
Human C20orf70 (His Tag) recombinant protein
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Description
C20orf70 belongs to the BPI/LBP/Plunc superfamily, Plunc family. PLUNC family is comprised by mucosal secretory proteins that are predicted to be structurally similar to lipid-binding and host-defense proteins including bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein. C20orf70 can be detected in submandibular gland. C20orf70 gene contains 9 distinct gt-ag introns. Transcription produces 6 different mRNAs, 4 alternatively spliced variants and 2 unspliced forms. There are 2 probable alternative promotors, 3 non overlapping alternative last exons and 4 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 3' end. 80 bp of this gene are antisense to spliced gene glopa, raising the possibility of regulated alternate expression. C20orf70 is expected to have molecular function (lipid binding) and to localize in extracellular region. It is a salivary protein of unknown function.
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Protein name
BPI fold-containing family A member 2
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Protein short names
SPLUNC2; BPIFA2E; BA49G10.1; PSP; BPIFA2; BPI FOLD CONTAINING FAMILY A; C20ORF70; MEMBER 2
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Uniprot ID
Q96DR5
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Gene Name
BPIFA2; C20orf70; SPLUNC2; UNQ510/PRO1025
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human C20orf70 (Q96DR5) (Met1-Ile249) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human C20orf70 consists of 242 amino acids and predicts a molecular mass of 26.5 KDa. It migrates as an approximately 35 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human BPIFA2 / C20orf70 Protein (His Tag) SDS-PAGE
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