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Product Name
Human BCL2L2/BCLW/KIAA0271 (His tag) recombinant protein
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Description
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
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Protein name
BCL2 like 2(BCL2L2)
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Protein short names
BCLW; KIAA0271
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Uniprot ID
Q92843
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human BCL2L2/BCLW/KIAA0271 Ala2-Thr172 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human BCL2L2/BCLW/KIAA0271 (His tag) recombinant protein
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