Human ASXL1/KIAA0978 (GST tag) recombinant protein

Cat.#: 518740

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Product Information

  • Product Name
    Human ASXL1/KIAA0978 (GST tag) recombinant protein
  • Documents
  • Description
    Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.
  • Protein name
    additional sex combs like 1, transcriptional regulator(ASXL1)
  • Protein short names
    KIAA0978
  • Uniprot ID
    Q8IXJ9
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human ASXL1/KIAA0978 Lys1477-Arg1541 is expressed with a GST tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human ASXL1/KIAA0978 (GST tag) recombinant protein

    Human ASXL1/KIAA0978 (GST tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"