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Product Name
Human ASS1/ASS (His tag) recombinant protein
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Description
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.
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Protein name
argininosuccinate synthase 1(ASS1)
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Protein short names
ASS
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Uniprot ID
P00966
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ASS1/ASS Met1-Lys412 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ASS1/ASS (His tag) recombinant protein
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