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Product Name
Human APOC2/APC2 (His tag) recombinant protein
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Description
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
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Protein name
apolipoprotein C2(APOC2)
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Protein short names
APC2
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Uniprot ID
P02655
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human APOC2/APC2 Met1-Glu82 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human APOC2/APC2 (His tag) recombinant protein
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