• Human ANGPTL8/C19orf80/RIFL (His tag) recombinant protein

Human ANGPTL8/C19orf80/RIFL (His tag) recombinant protein

Cat.#: 518019

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Product Information

  • Product Name
    Human ANGPTL8/C19orf80/RIFL (His tag) recombinant protein
  • Documents
  • Description
    The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proliferation is promising in diabetes therapy. Betatrophin treatment could supply or replace insulin injections by increasing the number of insulin-producing cells in diabetes.
  • Protein name
    angiopoietin like 8(ANGPTL8)
  • Protein short names
    C19orf80; RIFL; UNQ599; PRO1185
  • Uniprot ID
    Q6UXH0
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human ANGPTL8/C19orf80/RIFL Ala22-Ala198 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human ANGPTL8/C19orf80/RIFL (His tag) recombinant protein

    Human ANGPTL8/C19orf80/RIFL (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"