-
Product Name
Human ALOX15B / 15 Lipoxygenase 2 (His & GST Tag) recombinant protein
- Documents
-
Description
ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. ALOX15B converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. ALOX15B gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
-
Protein name
Arachidonate 15-lipoxygenase B
-
Protein short names
8S-LIPOXYGENASE; ARACHIDONATE OMEGA(6) LIPOXYGENASE; 15S-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE TYPE II; ALOX8; ARACHIDONATE 15-LIPOXYGENASE B; 15-LIPOXYGENASE 2; TYPE B; RP23-26L6.5; 8-LOX; ARACHIDONATE 15-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE 2; 15-LOX-B; ARACHIDONATE 8-LIPOXYGENASE; 8S-LOX; 15-LOX-2; SECOND TYPE; ALOX15B
-
Uniprot ID
O15296
-
Gene Name
ALOX15B
-
Source/Expression Host
Baculovirus-Insect Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human ALOX15B (AAH35217.1)( Met1-Ile676) was expressed the N-terminal polyhistidine-tagged GST tag at the N-terminus.
-
Protein Species
Human
-
Molecular weight
The secreted recombinant human ALOX15B consists of 913 amino acids and predicts a molecular mass of 103.7 KDa. The apparent molecular mass of the protein is approximately 93 KDa in SDS-PAGE under reducing conditions due to glycosylation.
-
Purity
> 90 % as determined by SDS-PAGE
-
Validations
Human ALOX15B / 15 Lipoxygenase 2 Protein (His & GST Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"