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Product Name
Human AKR1C3/DDH1/HSD17B5/KIAA0119/PGFS (His tag) recombinant protein
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Description
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.
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Protein name
aldo-keto reductase family 1 member C3(AKR1C3)
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Protein short names
DDH1; HSD17B5; KIAA0119; PGFS
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Uniprot ID
P42330
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human AKR1C3/DDH1/HSD17B5/KIAA0119/PGFS Met1-Tyr323 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human AKR1C3/DDH1/HSD17B5/KIAA0119/PGFS (His tag) recombinant protein
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