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Product Name
Human AGR2/AG2/UNQ515/PRO1030 (His tag) recombinant protein
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Description
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
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Protein name
anterior gradient 2, protein disulphide isomerase family member(AGR2)
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Protein short names
AG2; UNQ515; PRO1030
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Uniprot ID
O95994
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human AGR2/AG2/UNQ515/PRO1030 Arg21-Leu175 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human AGR2/AG2/UNQ515/PRO1030 (His tag) recombinant protein
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