• Hsp60.4 peptide

Hsp60.4 peptide

Not For Human Use, Lab Use Only.

Cat.#: 319193

Size:
Optional Service: TFA RemovalWhat's this?

Special Price 94.2 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Hsp60.4 peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    H-GMKFDRGYI-OH
  • Three letter code
    H-Gly-Met-Lys-Phe-Asp-Arg-Gly-Tyr-Ile-OH
  • Length (aa)
    9
  • Peptide Purity (HPLC)
    95.81%
  • Molecular Formula
    C49H75N13O13S
  • Molecular Weight
    1086.26
  • Source
    Synthetic
  • Additional Information
    GMKFDRGYI is a TCR-cross-reactive peptide encoded by mammalian heat shock protein 60. GMKFDRGYI was also capable of stabilizing HLA-E molecules on transfected K562 cells as well as on 721.221 cells. The hsp60.4 peptide (GMKFDRGYI) could bind to Qa-1b, but did not induce protection from CD94/NKG2A+ NK cells.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Jakob Michaëlsson, Cristina Teixeira de Matos, Adnane Achour, Lewis L. Lanier, Klas Kärre, Kalle Söderström; A Signal Peptide Derived from hsp60 Binds HLA-E and Interferes with CD94/NKG2A Recognition . J Exp Med 2 December 2002; 196 (11): 1403–1414.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"