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Product Name
Human FcERI / FCER1A (His Tag) recombinant protein
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Description
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
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Protein name
High affinity immunoglobulin epsilon receptor subunit alpha
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Protein short names
IMMUNOGLOBULIN E RECEPTOR; FCEPSILONRI; FCR-5; FC-EPSILON RI-ALPHA; FC EPSILON RI ALPHA-CHAIN; HIGH-AFFINITY; RP11-550P17.3; ALPHA POLYPEPTIDE; FC IGE RECEPTOR; OF MAST CELLS; IGE FC RECEPTOR SUBUNIT ALPHA; FCE1A; FCERI; HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA; HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT
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Uniprot ID
P12319
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Gene Name
FCER1A; FCE1A
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human FCER1A (P12319) (Met1-Gln205) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human FCER1A consists of 191 amino acids and predicts a molecular mass of 24.5 KDa. It migrates as an approximately 42-48 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human FcERI / FCER1A Protein (His Tag) SDS-PAGE
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