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Product Name
Human HS3ST1 (His Tag) recombinant protein
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Description
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
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Protein name
Heparan sulfate glucosamine 3-O-sulfotransferase 1
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Protein short names
3OST; 3-OST; D5WSU110E; 3OST1; HSG3OST
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Uniprot ID
O14792
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Gene Name
HS3ST1; 3OST; 3OST1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human HS3ST1 (AAH57803.1) (Arg21-His307) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human HS3ST1 consists 303 amino acids and predicts a molecular mass of 36 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Human HS3ST1 Protein (His Tag) SDS-PAGE
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