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Product Name
Human N6AMT1 (His Tag) recombinant protein
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Description
Heterodimeric methyltransferase that catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid.
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Protein name
HemK methyltransferase family member 2
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Protein short names
PRED28; N6AMT1; C21ORF127; N6AMT; MGC106447; 5830445C04RIK; MGC19995; HEMK2; M.HSAHEMK2P; MTQ2
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Uniprot ID
Q9Y5N5
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Gene Name
N6AMT1; C21orf127; HEMK2; PRED28
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human N6AMT1 (AAH11554.1) (Met 1-Ser 186) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human N6AMT1 comprises 196 amino acids and has a calculated molecular mass of 21.2 kDa. It migrates as an approximately 23 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human N6AMT1 / HEMK2 Protein (His Tag) SDS-PAGE
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