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  • H13N6 HA (His Tag) recombinant protein

H13N6 HA (His Tag) recombinant protein

Cat.#: 500198

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Product Information

  • Product Name
    H13N6 HA (His Tag) recombinant protein
  • Documents
  • Description
    Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
  • Protein name
    Hemagglutinin
  • Protein short names
    C-HA-RAS1; SPH; C-H-RAS; SPNA1; RASH1; AF093576; CTLO; HA; HRAS1; SPNA-1; C-BAS/HAS; IHJ; AI451697; NMF4; P21RAS; H-RASIDX; HAMSV
  • Uniprot ID
    Q5DL25
  • Gene Name
    HA
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Influenza A virus (A/black-headed gull/Sweden/1/1999(H13N6)) hemagglutinin (AAV91213.1) (Met1-Arg342), termed as HA1, was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    H13N6
  • Molecular weight
    The recombinant HA1 subunit of Influenza A virus (A/black-headed gull/Sweden/1/1999(H13N6)) consists 335 amino acids and predicts a molecular mass of 37.3 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Activity
    Measured by its ability to agglutinate guinea pig red blood cells.
    HA titer is 0.1-0.5μg/mL for 1%GRBC
  • Validations

    Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) / HA Protein (His Tag)

    Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) / HA Protein (His Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"