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  • H1N1 HA recombinant protein (C-His)
  • H1N1 HA recombinant protein (C-His)

H1N1 HA recombinant protein (C-His)

Cat.#: 514924

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Product Information

  • Product Name
    H1N1 HA recombinant protein (C-His)
  • Documents
  • Description
    The influenza viral Hemagglutinin (HA) protein is a homo trimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane.The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA0, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA0) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.
  • Protein short names
    Hemagglutinin, HA
  • Uniprot ID
    ABD62843.1
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Influenza A virus (A/Bel/1942 (H1N1)) hemagglutinin (ABD62843.1) (Met1-Gln529), termed as HA, was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    H1N1
  • Molecular weight
    The recombinant hemagglutinin of Influenza A virus (A/Bel/1942 (H1N1)) consists of 523 amino acids and predicts a molecular mass of 59.3 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    H1N1 HA Protein 15521

    H1N1 HA Protein 15521

    Influenza A H1N1 (A/Bel/1942) Hemagglutinin / HA Protein (His Tag)

    Influenza A H1N1 (A/Bel/1942) Hemagglutinin / HA Protein (His Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"