Human GPD1 / Glycerolphosphate Dehydrogenase 1 (His Tag) recombinant protein

Human GPD1 / Glycerolphosphate Dehydrogenase 1 (His Tag) recombinant protein

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• Material Safety Data Sheets (MSDS)

GPD1, also known as glycerolphosphate dehydrogenase 1, is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. GPD1 catalyzes the reversible redox conversion of dihydroxyacetone phosphate (DHAP), thus plays a critical role in carbohydrate and lipid metabolism. It also reduces nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. Meanwhile, GPD1 and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in GPD1 gene are a cause of transient infantile hypertriglyceridemia.

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD+]; GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1 (SOLUBLE); GDC-1; GLYCEROL PHOSPHATE DEHYDROGENASE 1; CYTOPLASMIC; GPD1; GLYCEROPHOSPHATE DEHYDROGENASE; AI747587; GPDH-C; GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]; GLYCEROLPHOSPHATE DEHYDROGENASE 1; GPD-C; CYTOPLASMIC ADULT; HTGTI; GDC1; MKIAA4010

P21695

GPD1

E. coli

A DNA sequence encoding the human GPD1(P21695) (Met1-Met349) was expressed with a polyhistidine tag at the N-terminus.

Human

The recombinant human GPD1 consists of 364 amino acids and predicts a molecular mass of 39.4 KDa. It migrates as an approximately 33-37 KDa band in SDS-PAGE under reducing conditions.

> 95 % as determined by SDS-PAGE