-
Product Name
Human GRIK2 (Fc Tag) recombinant protein
- Documents
-
Description
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).
-
Protein name
Glutamate receptor ionotropic, kainate 2
-
Protein short names
MRT6; AW124492; GLUK2; GLURBETA2; GLUR-6; GLR6; GLUR6; EAA4; GLUK6
-
Uniprot ID
Q8IY40
-
Gene Name
GRIK2; GLUR6
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human GRIK2 (NP_001159719.1) (Met1-Pro561) was expressed with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human GRIK2 consists 768 amino acids and predicts a molecular mass of 86.5 kDa.
-
Purity
> 90 % as determined by SDS-PAGE.
-
Validations
Human GRIK2 Protein (Fc Tag)
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"