gamma-glutamyl-cysteinyl-alanine peptide
Not For Human Use, Lab Use Only.
Cat.#: 300293
Special Price 76.1 USD
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Product Name
gamma-glutamyl-cysteinyl-alanine peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
H-ECA-OH
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Sequence
H-Glu-Cys-Ala-OH
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Length (aa)
3
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Peptide Purity (HPLC)
95.48%
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Molecular Formula
C11H19N3O6S
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Molecular Weight
321.35
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Source
Synthetic
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Form
Powder
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Description
gamma-glutamyl-cysteinyl-alanine was found in kidney bean (Phaseolus vulgaris).
Addition of a nearly tasteless aqueous extract isolated from beans (Phaseolus vulgaris L.) to a model chicken broth enhanced its mouthfulness and complexity and induced a much more long-lasting savory taste sensation on the tongue. gamma-glutamyl-cysteinyl-alanine is one of the key molecules inducing this taste-modifying effect.
Sensory analysis of aqueous solutions showed threshold concentrations between 3.3 and 9.4 mmol/L for an unspecific, slightly astringent sensation. And when added to a savory matrix such as sodium chloride and monosodium glutamate solutions or chicken broth, the detection thresholds of gamma-glutamyl-cysteinyl-alanine decreased significantly and remarkably enhanced mouthfulness, complexity, and long-lastingness of the savory taste were observed. -
Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
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References
- Dunkel A, Köster J, Hofmann T. Molecular and sensory characterization of gamma-glutamyl peptides as key contributors to the kokumi taste of edible beans (Phaseolus vulgaris L.). J Agric Food Chem. 2007 Aug 8;55(16):6712-9.
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About TFA salt
Trifluoroacetic acid (TFA) has a significant impact on peptides due to its role in the peptide synthesis process.
TFA is essential for the protonation of peptides that lack basic amino acids such as Arginine (Arg), Histidine (His), and Lysine (Lys), or ones that have blocked N-termini. As a result, peptides often contain TFA salts in the final product.
TFA residues, when present in custom peptides, can cause unpredictable fluctuations in experimental data. At a nanomolar (nM) level, TFA can influence cell experiments, hindering cell growth at low concentrations (as low as 10 nM) and promoting it at higher doses (0.5–7.0 mM). It can also serve as an allosteric regulator on the GlyR of glycine receptors, thereby increasing receptor activity at lower glycine concentrations.
In an in vivo setting, TFA can trifluoroacetylate amino groups in proteins and phospholipids, inducing potentially unwanted antibody responses. Moreover, TFA can impact structure studies as it affects spectrum absorption.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
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• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"